Striking basal ganglia imaging abnormalities in LGI1 ab faciobrachial dystonic seizures
نویسندگان
چکیده
Autoimmune encephalitis associated with antibodies targeting the neuronal surface antigen leucine-rich, glioma-inactivated 1 (LGI1) protein is accompanied by faciobrachial dystonic seizures (FBDS) in up to half of patients. These hallmark episodes can be mistaken for psychiatric disorders, particularly as the ictal episodes are usually not detectable with surface EEG electrodes. Accompanying imaging abnormalities help exclude psychiatric etiologies, localize the seizures, and improve our understanding of the pathogenesis. Herein, we present striking imaging abnormalities in a patient with FBDS from LGI1antibody encephalitis.
منابع مشابه
Basal ganglia T1 hyperintensity in LGI1-autoantibody faciobrachial dystonic seizures
OBJECTIVE To characterize the clinical features and MRI abnormalities of leucine-rich glioma-inactivated 1 (LGI1)-autoantibody (Ab) faciobrachial dystonic seizures (FBDS). METHODS Forty-eight patients with LGI1-Ab encephalopathy were retrospectively identified by searching our clinical and serologic database from January 1, 2002, to June 1, 2015. Of these, 26 met inclusion criteria for this c...
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